Keeping It Together with Marfan Syndrome – A Connective Tissue Disease

2010-03-16 | |
Last updated: 2010-03-16

What Are The Health Effects Of Having Marfan Syndrome?

The results of these genetic mutations to those with the condition are numerous problems with the body structure that can vary from mild to severe. People with Marfan Syndrome are typically tall with very long arms and frequently have a hunched back. Their fingers and wrists are also often very long and thin. Based on research from Pare Hospital in France, people with the condition also have a lower density of minerals in their bone.

Among the more than 30 known problems associated with the condition are scoliosis or a curved spine, weak muscle tone, dislocated eye lenses and joint problems. Internally, the condition can cause collapse of a lung, leaky heart valves, as well as aneurysms and ruptures of the aortic artery that carries blood out of the heart to the body. These heart problems are the most dangerous part of the condition and have led to numerous cases of basketball players collapsing and dying on the court.

Though the reasons are not yet understood, individuals with the condition also suffer from higher rates of migraines. Based on research lead by Amsterdam Academic Medical Center in 2009, those with Marfan Syndrome had a more than 40% higher risk of Migraines than the general population. Some of the migraines were also of the form often associated with brain aneurysms and stroke.

How Is Medical Science Helping Those With Marfan Syndrome?

With all the possible health risks associated with the condition, the 2008 discovery that the existing high blood pressure drug losartan is able to prevent expansion of the aortic artery is very good news. From 1972 to 1993, surgery and medical therapy increased the average life expectancy of people with Marfan Syndrome from 48 to 72 years and it is still climbing.

Now, with the research performed at John Hopkin’s Children’s Center, the study results indicate that the rate of enlargement of the aortic artery can be slowed by an average of 7 times or even halted. These findings will help to ensure that those with the Marfan Syndrome are not denied the chance to live life fully.

Do you or a loved one have Marfan Syndrome? Do you wish to find others who also have the condition? Consider joining the site and sharing your opinions in the forums.

Related Links

http://www.nhlbi.nih.gov/health/dci/Diseases/mar/mar_whatis.html
http://rheumatology.oxfordjournals.org/cgi/content/full/40/3/358
http://www.nlm.nih.gov/medlineplus/ency/article/000418.htm
http://www.internationaljournalofcardiology.com/article/S0167-5273(08)00750-X/abstract
http://marfan.stanford.edu/FAQ.html#How
http://pediatrics.aappublications.org/cgi/content/full/123/1/391#SEC4
http://www.hopkinsmedicine.org/hmn/F07/feature1.cfm
http://www.ncbi.nlm.nih.gov/pubmed/7810492
http://www.jtcvsonline.org/article/S0022-5223(07)01546-2/abstract
http://www.hopkinschildrens.org/drug-treatment-marfan-syndrome.aspx

Pages: 1 2

Tags: , , , , ,

Category: Disease Information, General Health, Symptom Information

Comments are closed.