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  February 21st, 2009

   The Last Jab for Diabetics?

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For insulin-dependent diabetics, pinpricks and needles are an unpleasant, but necessary part of daily life. The pinpricks are required to obtain a small blood sample in order to measure blood sugar while the needles are required to inject an appropriate amount of insulin so that the body's cells absorb the glucose out of the blood. This process must be repeated throughout the day since a diabetic with this condition essentially has to manually replace the natural functions of their damaged pancreas.


While many diabetics become used to all this poking, the reality is that this approach is crude and inconsistent. While a normal working pancreas is constantly adjusting the blood sugar levels, even diabetics who manage their blood sugar levels very well will have unhealthy blood sugar levels for periods of time that lead to accumulated damage to body tissues over the years.


The good news, however, is that the number of daily jabs that diabetics have to inflict upon themselves may soon reduce with the advent of some new technologies and some new research findings. More importantly, the control of blood sugar may just get a little easier and more stable to reduce the long term damage caused to the body.


To simplify measuring blood sugar, a few new technologies have been created or are in the works. Both technologies involve getting a tattoo, although one will leave the more conservative among us feeling a little less anxiety! The tattoos are real with glucose sensitive dyes being placed beneath the skin, but in one case they are visible in normal light, while in the other case are only visible under the fluorescent lights at the disco. In any case, however, the tattooed area won't attract much attention because the required size of the tattoo is only a few millimeters.


The technologies work by the dyes changing color or brightness depending on the glucose levels in the blood to act like your car's wiper fluid indicator while requiring no blood sample be extracted. Because the dyes are constantly indicating the blood sugar level, they can be checked regularly to enable much tighter controls of blood glucose.


With these technologies, those with diabetes can have a constant view of their blood sugar, but they would still need to inject insulin a number of times during the day. The potential for improvement here resides in reducing or eliminating the number of daily injections and that is where the research findings from scientists at UT Southwestern Medical Center are very interesting.


The findings published in the Proceedings of the National Academy of Sciences indicate that leptin, a hormone naturally produced by fat cells, was able to reduce the glucose levels in the blood of rodents for periods of time longer than the 3 or 4 hours that insulin is typically active. On top of this, leptin, it seems, might also be something that could be taken orally and could replace insulin injections according to the scientists involved in the study.


While studies on rodents don't automatically equate to a treatment for humans, the mention of clinical trials for leptin within the next year by the scientists publishing the study does suggest considerable promise.


Those with Type-1 Diabetes may soon be able to forget choosing a finger to prick and choosing where to inject the units of insulin. We can all look forward to respectfully saying, "Thank you Sir Banting for all you have done, but your services are no longer required".


Related Links:

http://i.gizmodo.com/5153677/tattoo-doubles-as-a-blood-glucose-level-monitor-rebellious-yet-cautious
http://www.technovelgy.com/ct/Science-Fiction-News.asp?NewsNum=1332
http://www.neatorama.com/2009/02/13/diabetes-monitoring-nanoparticle-tattoos/
http://www.technologyreview.com/biomedicine/22014/
http://www.medicalnewstoday.com/articles/139031.php
http://www.endocrineweb.com/insulin.html


tagstype 1 diabetes    insulin    leptin    injection    blood sugar    diabetes   





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  August 29th, 2010

   The Many Routes to Destination Constipation

Look a the side effects for a handful of medications and more likely than not, Constipation will be in the list. However, medical conditions can also slow the flow bringing discomfort and pain from this extremely common medical symptom.
tagsconstipation    digestive disorders    cramps    pain    digestion    side-effect   


  August 23rd, 2010

   Ending the Repetitive Strain and Pain of Technology

Since the time that there have been repetitive tasks, there has been Repetitive Strain Injuries (RSI), but with the adoption of an ever growing number of technologies in our daily lives, the number of ways in which technology can cause pain is growing.
tagsRSI    repetitive strain injury    carpal tunnel    wrist pain    RMI    CTD    overuse   


  August 15th, 2010

   The Rising Risks of Cholera in Pakistan's "Floo...

When floods happen, one of the most dangerous risks to the greatest number of people is the risk of Cholera. If untreated, the condition can rapidly be fatal so as the waters continue to remain high in Pakistan so do the risks of a Cholera pandemic.
tagsflood    natural disaster    cholera    water contamination    bacteria    bacterial infection   


  August 8th, 2010

   Understanding The Risks Of Balance Disorders

Though our sense of balance is fundamental to carrying on everyday activities, most of us are unaware of just how widespread issues of balance are. To minimize our risks it is important to understand the many ways our balance can be affected.
tagsbalance disorder    vestibular    falling injuries    dizziness    aging   


  August 1st, 2010

   In The Thick Of The Hunt For Huntington's Disease

From its initial identification as a genetic disorder involving one gene in 1993, the advances made in understanding Huntington's Disease continue to accumulate rapidly. This is good news because such progress is not typical of a rare disease.
tagshuntingtons    dementia    genetic disorder    medical science    degenerative    aging   





                 
                 
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